Abstract
Background: Esophageal Foreign Body (EFB) ingestion is a frequent
emergency, particularly in children and neurologically impaired adults. In
resource-limited settings like Eastern Nepal, optimal anaesthetic management
remains challenging due to infrastructure constraints and lack of standardized
protocols.
Methods: This observational study at a Nepalese tertiary hospital analysed
40 EFB cases (ages 1 to 75 years) over two months. Using convenience sampling,
we documented anaesthetic techniques, airway management and outcomes through
structured interviews and medical records.
Results: Paediatric cases comprised 55% of presentations. Coins
(27.5%), chicken bones (17.5%) and fish bones (15%) were most common, primarily
lodged in upper esophagus (37.5%). Intravenous anaesthesia (60%) surpassed
general anaesthesia (40%), with nasopharyngeal tubes (65%) preferred over
endotracheal intubation (35%). Propofol (75%) and fentanyl (55%) were mainstay
medications. Mean procedure duration was 15 to 20 minutes with Para oxygenation
in 67.5% cases. Complication rate was 17.5% (desaturation 10%, laryngospasm
5%).
Conclusion: Resource-adapted anaesthetic approaches demonstrated safety in EFB removal, though technique variability highlights need for standardized protocols. Findings support context-specific guideline development for low-resource settings.
Keywords: Foreign body, Esophagus, Anaesthetic management, Endoscopic removal, Resource limited setting
1. Introduction
Esophageal Foreign Body (EFB)
ingestion is a frequent clinical emergency, particularly in paediatric
populations, though adults with neurological or psychiatric conditions are also
at risk1. Delayed or improper
management can lead to severe complications such as perforation, mediastinitis
or aspiration pneumonia, necessitating prompt and safe removal2. While endoscopic extraction remains the
gold standard, anaesthetic management plays a critical role in ensuring
procedural success and patient safety3.
However, the choice of anaesthesia-General Anaesthesia (GA), intravenous
sedation or other techniques-varies widely depending on patient factors,
foreign body characteristics and available resources4.
In resource-limited settings like Eastern Nepal, the lack of standardized anaesthetic protocols poses significant challenges5. Limited infrastructure, varying expertise and scarcity of studies evaluating optimal techniques contribute to inconsistent practices6. This study aims to assess the current anaesthetic approaches for EFB removal in a tertiary care centre in Eastern Nepal, evaluating their safety, efficacy and challenges. Moreover, this study will contribute to establishing evidence-based anaesthetic protocols for esophageal foreign body removal, improving patient outcomes in Eastern Nepal. By analysing demographic trends, procedural outcomes and complications, this research seeks to provide evidence-based insights to improve anaesthetic management in similar low-resource settings.
2. Methods
This prospective,
observational study was conducted in the Emergency Department of a tertiary
care teaching hospital in eastern Nepal, involving patients aged 1 to 75 years
with a diagnosis of esophageal foreign body impaction. Using a convenience
sampling method, all eligible cases presenting over a two-month period were
included, resulting in a final sample size of 40 participants.
We acknowledge this as a limitation and recommend future studies with power
calculations for stronger evidence. The study aimed to assess the demographic and clinical characteristics
of patients with esophageal foreign bodies in this setting. Ethical approval
was obtained and data were collected through structured interviews and medical
record reviews. Written informed consent was taken from
adult patients/parents of paediatric cases.
2.1. Inclusion criteria
Patients with age group 1-75 years undergoing
esophageal foreign body removal.
Patients requiring general anaesthesia or
sedation.
2.2. Exclusion criteria
Known allergies to anaesthetic agents.
Patients with multiple comorbidities or those
who are unfit for anaesthesia.
Clinical history and examination finding along with the peri-operative anaesthesia record of the study participants were noted in proforma Data was entered in Microsoft Excel and analysed using SPSS version 2.0. The categorical variables expressed in frequency and percentages and the association between the two groups was calculated using Chi-square test. The quantitative variables were expressed as mean (standard deviation). A p-value of less than 0.05 was considered as statistically significant.
3. Results
The findings of this observational study provide valuable insights into the anaesthetic management of Esophageal Foreign Body (EFB) removal in a resource-limited tertiary care centre in Eastern Nepal. The study population demonstrated a clear paediatric predominance (55%), with children aged 1 to 12 years being most affected, which aligns with global epidemiological trends of EFB ingestion (Table 1). Coins emerged as the most commonly encountered foreign bodies (27.5%), followed by chicken bones (17.5%) and fish bones (15%), reflecting patterns seen in similar developing world settings (Table 1). The anatomical distribution showed that most impactions occurred at the upper esophagus (37.5%) and pharyngoesophageal junction (35%), consistent with known physiological narrowing points in the esophageal lumen (Table 1).
Table 1: Patient Demographics & Foreign Body Characteristics.
|
Age Group |
||
|
Pediatric (1-12 years) |
22 |
55% |
|
Adult (>12 years) |
18 |
45% |
|
Common Foreign Bodies |
||
|
Coins |
11 |
27.50% |
|
Chicken bones |
7 |
17.50% |
|
Fish bones |
6 |
15% |
|
Dentures |
4 |
10% |
|
Others (plastic, meat) |
12 |
30% |
|
Site of Impaction |
||
|
Upper esophagus |
15 |
37.50% |
|
Pharyngoesophageal junction |
14 |
35% |
|
Mid/lower esophagus |
11 |
27.50% |
Regarding anaesthetic approaches, Intravenous Anaesthesia (IVA) was the preferred technique in 60% of cases, likely due to its rapid onset, short duration and lower resource requirements compared to General Anaesthesia (GA), which was administered in 40% of cases (Table 2). GA was preferred in paediatric patients, type of foreign body which included fish bone and sharp chicken bone (which has high chance of causing perforation and removal may require longer duration) and site of impaction which included pharyngoesophageal junction and upper esophagus. Airway management predominantly utilized nasopharyngeal tubes (65%) rather than cuffed endotracheal tubes (35%), possibly reflecting the shorter procedure durations and less invasive nature of these cases. Pharmacologically, propofol (75% of cases) and fentanyl (55%) were the most frequently administered agents, with mean dosages falling within typical therapeutic ranges, while succinylcholine was reserved for GA cases requiring muscle relaxation (Table 2). Propofol in the dose of 0.5-2.5mg/kg, fentanyl in the dose of 0.5-2mcg/kg and ketamine in the dose of 0.5-2mg/kg was used in cases where IVA was used. Spontaneous respiration was maintained when IVA was used. Meanwhile succinylcholine in the dose of 1-2mg/kg was used in addition to the drugs used in IVA, was used in cases where GA was given.
Table 2: Anesthetic Methods & Medications Used.
|
Variable |
Frequency (n=40) |
Percentage (%) |
Mean Dosage (Range) |
|
Anesthesia Type |
|||
|
IV Anesthesia |
24 |
60% |
- |
|
General Anaesthesia |
16 |
40% |
- |
|
Airway Management |
|||
|
Nasopharyngeal tube (NP) |
26 |
65% |
- |
|
Cuffed ETT |
14 |
35% |
- |
|
Medications Used |
|||
|
Propofol |
30 |
75% |
50-100 mg |
|
Ketamine |
18 |
45% |
20-50 mg |
|
Fentanyl |
22 |
55% |
15-50 mcg |
|
Succinylcholine |
10 |
25% |
0-100 mg |
Emergency airway equipment (laryngoscopes, supraglottic devices) and personnel trained in airway rescue were always available. A backup plan (e.g., rapid intubation or surgical airway) was in place for airway obstruction. Procedural outcomes were generally favourable, with 82.5% of cases completed within 20 minutes and a relatively low overall complication rate of 17.5% (Table 3). The most common complications included minor desaturation (10%) and laryngospasm (5%), with no cases of esophageal perforation reported (Table 3). The frequent use of Para oxygenation (67.5%) likely contributed to the prevention of more severe hypoxic events (Table 3). These results suggest that while current anaesthetic practices in this setting are generally safe and effective, the observed variability in techniques underscores the need for standardized protocols, particularly in resource-constrained environments where advanced airway equipment and specialized personnel may be limited. While we have outlined some criteria to decide between IVA and GA, detailed protocol and guideline regarding the management of such cases have to be formulated. The study highlights both the adaptability of anaesthetic providers in such settings and the potential for further optimization of care pathways for EFB removal.
Table 3: Procedure Duration & Complications.
|
Variable |
Frequency (n=40) |
Percentage (%) |
|
Procedure Duration |
||
|
<15 minutes |
18 |
45% |
|
15-20 minutes |
15 |
37.50% |
|
>20 minutes |
7 |
17.50% |
|
Paraoxygenation used |
27 |
67.50% |
|
Complications |
||
|
Minor desaturation |
4 |
10% |
|
Laryngospasm |
2 |
5% |
|
Bleeding |
1 |
2.50% |
|
Perforation |
0 |
0 |
4. Discussion
This study provides
important insights into anaesthetic management for Esophageal Foreign Body (EFB)
removal in a resource-limited tertiary care center in Eastern Nepal. The
predominance of paediatric cases (55%) and coins as the most common foreign
body (27.5%) aligns with global trends, where children are at higher risk due
to accidental ingestion2,3. The
frequent impaction at the upper esophagus (37.5%) and pharyngoesophageal
junction (35%) supports existing anatomical studies highlighting these regions as
natural narrowing sites4.
The preference for Intravenous
Anaesthesia (IVA) (60%) over General Anaesthesia (GA) (40%) reflects pragmatic
decision-making in resource-constrained settings, where IVA offers faster
recovery and lower costs5. The
predominant use of Nasopharyngeal (NP) tubes (65%) rather than endotracheal
intubation (35%) suggests a balance between airway security and procedural
efficiency, particularly given the short mean procedure duration (15–20
minutes)1. The common use of propofol
(75%) and fentanyl (55%) is consistent with global sedation practices for
endoscopic procedures, while succinylcholine (25%) was appropriately reserved
for GA cases requiring muscle relaxation6,7.
The low complication rate
(17.5%), with minor desaturation (10%) and laryngospasm (5%) being the most
frequent, indicates that current anaesthetic practices are relatively safe.
However, the absence of standardized protocols may contribute to variability in
technique selection. The frequent application of Para oxygenation (67.5%)
likely contributed to preventing severe hypoxia, reinforcing its value in
sedation-assisted endoscopy8. The
lack of standardized guidelines leads to inconsistent practices, especially in
low-resource settings9, while
limited access to advanced airway devices (e.g., video laryngoscopes) may
hinder optimal airway management10.
Additionally, training gaps among anaesthesia providers in rural areas could
delay emergency interventions11. limitations
(small sample, single-centre data) will be further emphasized.
A call for multicentre
validation studies will be added to the conclusion.
Future research should prioritize multicentre validation studies and developing evidence-based protocols tailored to resource-limited environments to improve patient outcomes.
5. Summary
This observational study
evaluated anaesthetic management for Esophageal Foreign Body (EFB) removal in a
tertiary care centre in Eastern Nepal. Among 40 patients (55% paediatric),
coins (27.5%) were the most common foreign bodies, primarily lodged in the
upper esophagus (37.5%). Intravenous anaesthesia (60%) with nasopharyngeal
airways (65%) was preferred over general anaesthesia, utilizing propofol (75%)
and fentanyl (55%) most frequently. Procedures averaged 15 to 20 minutes with a
17.5% complication rate (primarily minor desaturation). The findings demonstrate
safe, resource-adapted practices while highlighting the need for multicentre
validation studies and standardized protocols in low-resource settings to optimize EFB removal
outcomes. Despite having some limitations including small sample size and
single centre study, this study provides valuable insights for improving anaesthetic
management in similar healthcare environments.
6. References