Case Report

Case Report of Broken Tip of Thrombus Aspiration Catheter in Acute Coronary Syndrome in Patient with Heart Block

Authors: Tayeb Ali Bafadhl

Publication Date: 02 February, 2026

DOI: https://doi.org/10.51219/MCCRJ/Tayeb-Ali-Bafadhl/435

Citation: Bafadhl TA. Case Report of Broken Tip of Thrombus Aspiration Catheter in Acute Coronary Syndrome in Patient with Heart Block. Medi Clin Case Rep J 2026;4(1):1577-1580.

Copyright:Bafadhl TA., This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

We describe 67 years old male patient presenting with acute coronary syndrome (acute inferior ST elevation) with complete heart block. primary percutaneous coronary intervention decided with temporary pacemaker insertion. In view thrombus burden lesion in proximal right coronary artery. we did thrombus aspiration by using thrombus aspiration catheter). After successfully aspirating thrombus, resistance felt on withdrawal of the aspiration catheter. Tip of the thrombus aspiration catheter was broken and retained in the guide wire at the level of proximal right coronary artery. The broken tip of thrombus aspiration catheter was successfully retrieved percutaneously.

Keywords: Coronary Syndrome; ST elevation; Catheter

Introduction

In ST elevation myocardial infraction (STEMI), percutaneous coronary intervention is superior to thrombolysis in terms of in-hospital mortality, re infarction and stroke¹. Coronary atherosclerotic plaque rupture with thrombus formation being the basic pathophysiologic phenomenon in acute myocardial infarction, prevalence of thrombus is very much commonly seen in STEMI compare to non-ST elevation myocardial infarction (NSTEMI)².

Thrombus aspiration in patients with high thrombus burden can decrease thrombus burden, lower rates of distal embolization, improve thrombolysis in myocardial infarction- 3 flow, reduce the incidence of no reflow, improve microvascular perfusion and consequently improve clinical outcomes. However, >2 dozen randomized trials have compared the outcomes of routine thrombus aspiration with primary percutaneous coronary intervention (PCI) alone in patients with ST- segment– elevation myocardial infarction (STEMI) and have not shown a consistent reduction in cardiovascular outcomes. As such, routine thrombus aspiration during primary PCI is not recommended by guideline committees (class III, 2021 American College of Cardiology/American Heart Association guidelines or 2017 European Society of Cardiology guidelines)^3,4.

Case Report
Male patient aged 67 years old with history of diabetes Mellitus type II (DM), presented to emergency department of private hospital with central chest pain increase in intensity 3 hours before arrival with history of sweating and nausea. ECG done on arrival (Figure 1).

Figure 1: ECG at presentation of the patient in ER in private hospital

The patient was subsequently admitted to the intensive care unit (ICU). On arrival, vital signs were as follows: blood pressure 90/60 mmHg, heart rate 60 beats/min and temperature 37 °C. Physical examination revealed no pallor or jaundice, no lower-limb edema and intact peripheral pulses. Abdominal examination showed no organomegaly. Chest examination was unremarkable with normal breath sounds. Cardiac examination demonstrated normal first and second heart sounds with no added sounds or murmurs.

Because the patient’s chest pain had decreased in intensity, thrombolytic therapy was unfortunately not administered. In addition, the admitting hospital lacked percutaneous coronary intervention (PCI) capability. Consequently, conservative management was initiated, including antiplatelet therapy, anticoagulation and statin therapy. The patient remained in the ICU for one day.

On the following day, the patient developed dizziness and recurrent episodes of shortness of breath. He requested expert consultation and was transferred to Nabdh Al-Hayat Cardiac Center (NCC) in Mukalla for further evaluation and management.

At NCC, reassessment revealed significant hemodynamic deterioration. Vital signs were as follows: blood pressure 80/50 mmHg, heart rate 40 beats/min and temperature 37°C. Electrocardiography was performed (Figure 2). Bedside transthoracic echocardiography demonstrated normal left-sided cardiac structure with preserved left ventricular systolic function, no resting regional wall-motion abnormalities and no mitral regurgitation. No mechanical complications were identified, including ventricular septal rupture, free-wall rupture or papillary muscle dysfunction. However, the right ventricle was dilated with global hypokinesia.

Figure 2: ECG of the patient at presentation to NCC

Primary percutaneous coronary intervention (PCI) was decided and the catheterization laboratory team was immediately activated. A trans-femoral venous approach was used for temporary pacemaker insertion, which was successfully established at a fixed rate of 60 beats/min. An initial attempt at right radial artery puncture for coronary angiography was unsuccessful; therefore, crossover to the right femoral artery was performed.

Coronary angiography was carried out using a 6-Fr diagnostic left Judkins catheter, which revealed an atherosclerotic left coronary system. A right Judkins guiding catheter was then used to cannulate the right coronary artery (RCA), demonstrating total occlusion of the proximal RCA with a high thrombus burden. The occluded segment was successfully crossed with a 0.014-inch BMW PTCA floppy guidewire. Limited thrombus aspiration was achieved after five passes using a 6-Fr Export aspiration catheter (Medtronic), as shown in (Figure 3). Control angiography of the RCA after thrombus aspiration demonstrated TIMI I flow. Subsequently, a 1.25 × 10 mm Sprinter balloon (Medtronic Inc.) was advanced over the guidewire for balloon predilatation. Upon reaching the proximal RCA, three radiopaque markers were visualized instead of the expected two (Figure 4). This immediately raised suspicion of device fracture. Careful inspection of the Export catheter, which had just been withdrawn from the guiding catheter and was lying on the table, confirmed loss of its distal tip. This represented a precarious situation, with a thrombogenic broken catheter fragment retained within a thrombus-laden coronary artery and loss of operator control over the fragment.

Given the very short distance between the distal balloon marker and the third radiopaque marker, it was inferred that only the distal tip of the Export catheter had fractured (Figure 5). An attempt to advance a smaller 1.0 × 10 mm Sprinter balloon distal to the retained fragment over the original guidewire was unsuccessful. Therefore, a second BMW PTCA guidewire was advanced into the distal RCA. A 2.0 × 12 mm Sprinter PTCA balloon was then advanced and positioned distal to the fractured catheter tip. The balloon was inflated to 8 atm and gently withdrawn from the mid to proximal RCA, successfully entrapping and retrieving the broken Export catheter tip into the guiding catheter.

The entire system, including the guiding catheter, both BMW PTCA guidewires, the balloon and the fractured aspiration catheter tip, was removed en bloc. The guiding catheter was flushed with heparinized saline and the retrieved broken catheter tip was clearly identified. The RCA was subsequently re-engaged using a new JR 3.5 guiding catheter and a fresh BMW PTCA guidewire successfully crossed the proximal RCA lesion. Predilatation was performed using a 2.0 × 12 mm Sprinter balloon, restoring TIMI III flow. A 3.0 × 30 mm drug-eluting stent was then deployed in the proximal RCA and inflated to 14 atm. Final angiography demonstrated TIMI III flow with good stent expansion and no evidence of edge dissection (Figure 6).

Figure 3: Thrombotic materials retrieved from RCA

Figure 4: Knob is noticed of the broken tip of export catheter (aspiration catheter) in proximal segment of RCA

Figure 5: Shaft of aspiration export catheter without tip

Discussion

The incidence of broken or retained percutaneous coronary intervention (PCI) hardware in earlier literature is approximately 0.2%⁵. Although significant refinement in device design has occurred over the past decade, the increasing number and complexity of percutaneous coronary procedures continue to be associated with occasional intravascular hardware failure. Several reports have described successful retrieval of fractured catheters, guidewires, balloons and both expanded and unexpanded stents from the intracoronary circulation using various techniques^5-7. Familiarity with these retrieval methods is essential, as no single technique is universally effective in all clinical scenarios.

Cagdas Akgullu, et al.⁸ reported a case of a trapped thrombus aspiration catheter in a coronary artery caused by rupture of the main shaft and twisting over the guidewire; the device was successfully removed by withdrawing the entire system. Other case reports have described complications related to thrombus aspiration catheters, including thrombus formation in the left main coronary artery and inadvertent coronary endarterectomy using the Thrombuster III GR catheter^9,10.

A review of 48 case reports involving a total of 67 patients with guidewire entrapment showed that 41.8% were managed by percutaneous extraction, 43.3% required surgical intervention and 14.9% were treated conservatively. Various percutaneous retrieval techniques have been described, including stenting the fragment against the vessel wall, snare loop capture, double- or triple-wire techniques, use of a bioptome, Tornus microcatheter, deep guide catheter wedging with balloon inflation and pigtail catheter manipulation¹¹.

In a prior report assessing the prevalence and outcomes of fractured PCI hardware, 12 out of 5,400 percutaneous transluminal coronary angioplasty (PTCA) procedures were complicated by retained components, including guidewire fragments, balloon catheters and guide catheters¹². Follow-up of patients with retained guidewire fragments revealed no clinical sequelae over a period ranging from 6 to 60 months, suggesting that management decisions should be individualized. Not all cases of retained hardware necessitate coronary artery bypass grafting (CABG), particularly when fragments are located in chronically occluded or distal vessels¹². Additional reports have documented successful retrieval of an FFR wire tip using an angiographic catheter (Slip-Cath) via the mother–child technique¹³, as well as balloon assisted extraction of a fractured Export catheter¹⁴.

Retained intracoronary hardware can act as a nidus for thrombus formation, potentially leading to acute vessel occlusion, myocardial infarction, arrhythmias, coronary perforation or embolic events¹⁵. Therefore, removal of the fractured fragment is generally recommended. In our patient, the presence of a thrombogenic milieu with thrombus formation proximal to the broken catheter significantly increased the risk of further thrombus propagation, making prompt retrieval of the fractured Export catheter tip imperative.

Potential causes of retained PCI hardware include excessive torquing, forceful catheter withdrawal, improper handling, device reuse, manufacturing defects, inadvertent advancement of large-caliber catheters through smaller access sheaths, polymer aging or a combination of these factors.

References

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Case Report of Broken Tip of Thrombus Aspiration Catheter in Acute Coronary Syndrome in Patient with Heart Block

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