Commentary
Commentary: Erythrasma Capitis and Hair Loss – An Under Diagnosed Entity?
Authors: Rauno J. Harvima* and Ilkka T. Harvima
Publication Date: 03 October, 2025
DOI:
https://doi.org/10.51219/MCCRJ/Rauno-J-Harvima/402
Citation:
Harvima RJ, Harvima IT. Commentary: Erythrasma Capitis and Hair Loss – An Under Diagnosed Entity? Medi Clin Case Rep J 2025;3(4):1427-1428.
Copyright:© 2025 Harvima RJ, et al., This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract
Corynebacterium
minutissimum causing erythrasma is considered to belong to normal skin flora.
The locations are commonly nasolabial folds, groin, axillae, intergluteal
folds, submammary region and interdigital spaces of the toes. There is only one
case report of two young women on Corynebacterium in the scalp, causing diffuse
and patched hair loss, thus it might give the possibility of underdiagnosis. In
addition oral antibiotic treatments for various infections and acne could,
thus, proactively or preventively lower the risk of scalp erythrasma with rare
outcome.
Keywords: Erythrasma, Diffuse
Patched Hair Loss; Eczema; Corynebacterium; Treatment
Erythrasma
in the Body
Corynebacteriium
minutissimum causing erythrasma is considered to belong to normal skin flora.
The locations are commonly nasolabial folds, groin, axillae, intergluteal
folds, submammary region and interdigital spaces of the toes. It can be
detected by UV lamp (Wood’s illumination lamp) as brick tile-red or coral-red
color in a dark room. Corynebacteria can be cultivated by a special procedure
and it is detectable by histology. Usually, mild topical antibacterial
treatments are used, e.g., fucidic acid, clindamycin, mupirosin, clotrimazole
or miconazole cream or oral and topical erythromycin and oral tetracyclin1-4. Oral
treatments include a single dose of 1g clarithromycin, erythromycin 250 mg QID
for 14 days or tetracyclin 250 mg QID for 14 days1. However, there are only
one case report on Corynebacterium minutissimum in the scalp5. Also, the
Braun-Falco’s or Rook’s Textbook of Dermatology do not reveal whether it could
cause any effect in the scalp, especially hair loss3,4.
Erythrasma
Capitis Cases
We published a case report5 of two cases of a 16-year and 21-year-old women who had diffuse
hair loss with eczema or patches for about 2 months, respectively. Studies
revealed excessive amounts of Corynebacteria in the scalp by histology and
Corynebacterium minutissimum in the bacterial culture. Other possible causes
like Treponema pallidum were excluded. Both patients were treated by
erythromycin for 2 months. At the follow-up their hairs were noted to have
grown fully but curly.
Conclusion
and Discussion
It could
be possible that the role of Corynebacteria might be underestimated and
underdiagnosed. Our 2 female cases with a short period of hair loss suggests to
take into account the possibility of Corynebacteria. The patched type may be
mixed with alopecia areata.
Corynebacteria are sensitive also for tetracyclines. Thus, it is
emphasizing to speculate whether erythmasma capitis with hair loss would be
treated “accidentally” proactively or preventively by tetracyclines used for
common acne for much longer time than suggested 2 weeks for erythrasma of body
areas except scalp. Also, other antibiotic treatments might have a similar
preventive effect. This could be a target for a wider study.
Sources
of Support
None.
Conflict
of Interest
None.
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O, Plewig G, Wolf HH, Burgdorf WHC. 2nd, Completely Revised Edition. Springer,
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Champion, JL Burton, FJG Ebling (Eds.), 5th Edition. Blackwell, London. Chapter
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RJ, Harvima IT. Erythrasma Capitis and Diffuse Hair Loss with Patches and
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