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Research Article

Correlation Between Osteoarthrosis and Post-Activity Symptom Relief


Abstract
This retrospective study explored the correlation between osteoarthrosis and post-activity symptom relief and evaluated activity-optimizing nursing interventions in 60 patients with osteoarthrosis. Patients were divided into responsive group (n=35, ≥50% symptom reduction post-activity) and non-responsive group (n=25, <50% reduction), with each group split into intervention (responsive: n=18; non-responsive: n=13) and control (responsive: n=17; non-responsive: n=12) subgroups. Intervention subgroups received activity-optimizing nursing (individualized activity prescription, timing adjustment, intensity modulation), while controls received routine care. Primary outcomes included correlation between osteoarthrosis severity (Kellgren-Lawrence grade) and relief duration and post-intervention relief maintenance rate at 12 weeks. Secondary outcomes included pain visual analog scale (VAS) change, joint stiffness duration and activity adherence rate. Results showed significant negative correlation between Kellgren-Lawrence grade and relief duration (r=-0.68, p<0.01). Intervention subgroups had higher maintenance rate (responsive: 83.3% vs 47.1%; non-responsive: 61.5% vs 25.0%, p<0.05). Activity-optimizing nursing enhances post-activity relief in osteoarthrosis patients, particularly those with mild-to-moderate disease.

Keywords:
Osteoarthrosis; post-activity symptom relief; Kellgren-lawrence grade; Mild-to-moderate disease

Introduction

Post-activity symptom relief is a distinctive feature in 40-50% of osteoarthrosis patients, characterized by reduced pain and stiffness after moderate activity due to improved joint lubrication and muscle warming1. However, this phenomenon diminishes with disease progression, as severe joint damage leads to activity-induced exacerbation rather than relief2. This study investigates the osteoarthrosis-post-activity relief association and evaluates nursing interventions to optimize this effect, addressing the lack of personalized activity protocols3.

Methods
Study design and participants
Retrospective analysis of 60 patients with radiographically confirmed osteoarthrosis (knee: 42 cases, hip: 18 cases). Inclusion criteria: age 45-80 years; Kellgren-Lawrence grade I-IV; ability to perform basic activities. Responsive group defined as ≥50% reduction in VAS pain within 30 minutes post-activity (walking 500m). Exclusion criteria: inflammatory arthritis, severe cardiovascular diseases and joint replacement history.

Grouping & interventions
Control subgroups: Routine care (general activity advice, pain assessment).

Intervention subgroups: Added activity-optimizing interventions:
• Individualized activity prescription: Tailored to joint type (knee: cycling; hip: swimming) and baseline function.
• Timing adjustment: Scheduling activities during peak stiffness periods (morning for 72% of patients) to maximize relief.
• Intensity modulation: Starting with 5-minute warm-up, maintaining Borg scale 3-4 (moderate exertion) and 5-minute cool-down.
• Symptom monitoring: Teaching patients to track relief duration/intensity via mobile app logs.

Outcome measures
• Primary: Correlation between Kellgren-Lawrence grade and initial relief duration; 12-week relief maintenance rate.
• Secondary: VAS pain change (0-10), morning stiffness duration (mins) and weekly activity adherence (≥5 sessions/week).

Statistical analysis
SPSS 26.0 used for Pearson correlation, χ² tests and independent t-tests. p<0.05 was significant.

Results
Osteoarthrosis-post-activity relief relationship and baseline data
Significant negative correlation between Kellgren-Lawrence grade and relief duration (r=-0.68, p<0.01). Responsive group had lower initial Kellgren-Lawrence grade (Table 1).

Table 1:
Baseline Characteristics

Characteristics

Responsive Group (n=35)

Non-Responsive Group (n=25)

p-value

Age (years, x̄±s)

62.3±8.5

64.1±7.9

0.41

Male gender, n(%)

19(54.3)

13(52.0)

0.87

Affected joint (knee/hip)

25/10

17/8

0.83

Kellgren-Lawrence grade (x̄±s)

1.8±0.7

3.1±0.8

<0.001

Initial VAS (pre-activity, x̄±s)

6.2±1.4

6.5±1.3

0.45

Relief duration (mins, x̄±s)

42.5±11.3

12.8±7.6

<0.001

Morning stiffness (mins, x̄±s)

38.2±10.5

41.3±11.2

0.32


Primary outcome
Severity association: Each 1-grade increase in Kellgren-Lawrence grade correlated with 18.2-minute reduction in relief duration (p<0.001).
Intervention effect: Intervention subgroups showed higher maintenance rate (Table 2).


Table 2:
12-Week Relief Maintenance Rate

Group

Intervention

Control

p-value

Responsive Group (n=35)

15/18(83.3%)

8/17(47.1%)

0.016

Non-Responsive Group (n=25)

8/13(61.5%)

3/12(25.0%)

0.042


Secondary outcomes

Intervention subgroups demonstrated greater improvements in all secondary measures (Table 3).

Table 3: Secondary Outcomes at 12 Weeks

Outcome

Responsive Group

Non-Responsive Group

p-value (intervention effect)

VAS reduction (post-pre, x̄±s)

Intervention:4.8±1.1

Intervention:2.3±0.9

<0.001

 

Control:2.6±1.0

Control:1.1±0.8

-

Stiffness duration reduction (mins)

Intervention:28.5±8.3

Intervention:15.2±7.1

<0.001

 

Control:14.2±7.5

Control:6.8±5.3

-

Activity adherence, n(%)

Intervention:16(88.9%)

Intervention:10(76.9%)

0.038

 

Control:9(52.9%)

Control:5(41.7%)

-


Discussion
This study confirms post-activity relief is inversely correlated with osteoarthrosis severity, consistent with preserved joint mobility in mild disease allowing beneficial lubrication and muscle activation4. The 3.3-fold longer relief duration in the responsive group aligns with data that severe joint space narrowing impairs mechanical benefit from activity5.

 

Activity-optimizing interventions enhanced relief through personalized prescription-matching activity type to joint biomechanics maximized chondrocyte nutrient diffusion6. Timing adjustments capitalized on diurnal rhythm of joint fluid viscosity, while intensity modulation prevented overloading7. Notably, 61.5% of non-responsive intervention patients achieved partial relief, suggesting even severe cases benefit from optimized activity8.

 

Limitations include reliance on self-reported relief and lack of objective joint fluid analysis. Future studies should measure synovial fluid viscosity changes post-activity.

 

Conclusion
Osteoarthrosis severity inversely correlates with post-activity symptom relief. Activity-optimizing nursing interventions effectively enhance relief maintenance, reduce pain/stiffness and improve adherence, with efficacy across disease stages. These strategies are critical for leveraging the therapeutic potential of activity in osteoarthrosis management.

 

References

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